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Enteric (typhoid) fever

General health information, not a diagnosis. In an emergency, call 102. Always consult a qualified health professional.

SmartAnalysis by DigiNepal SI

Enteric (typhoid) fever is an infectious condition assessed by SI. generated by SI from cited sources · general information, not a diagnosis · consult a health professional

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · https://www.cdc.gov/typhoid-fever/; https://www.who.int/news-room/fact-sheets/detail/typhoid; https://www.mayoclinic.org/search/search-results?q=Enteric%20%20fever; Guideline: WHO typhoid guidance 2018; https://edcd.gov.np

What it is

Enteric (typhoid) fever is an infectious condition assessed by SI.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Symptoms

Fever that climbs over several days, headache, weakness, stomach pain, loss of appetite, constipation or diarrhoea, sometimes a rose-coloured rash.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Causes

Salmonella Typhi (and Paratyphi) bacteria from food or water contaminated with faeces.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

When to seek care

EMERGENCY, go now: severe or sudden belly pain, vomiting blood, black stools, confusion, very high fever not settling. See a clinician for fever lasting more than 3 days.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Diagnosis

Blood culture taken before antibiotics is the reference test. The Widal test is unreliable on its own.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Care & treatment

Antibiotics chosen by a clinician based on local resistance patterns; finish the full course. Drug-resistant typhoid is increasing in South Asia. No dosing information is given here.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Prevention

Safe drinking water (boil, filter or treat), hand washing, well-cooked food, typhoid conjugate vaccine.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Nepal notes

Common in Nepal year round, peaking in the pre-monsoon and monsoon months, especially in the Kathmandu valley and Terai. Typhoid conjugate vaccine was added to Nepal's routine immunisation in 2022.

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

Clinical guideline

WHO typhoid guidance 2018

Sources: SI, NLM MedlinePlus, CDC, WHO (paraphrased) · Reference · US CDC · World Health Organization (WHO) · Mayo Clinic · EDCD — Epidemiology & Disease Control Division (Nepal)

⚠️ Red-flag signs — seek urgent care

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Text: SI summary in its own words (CC BY 4.0) with NLM MedlinePlus public-domain summary; facts checked against WHO fact sheets (CC BY-NC-SA 3.0 IGO, paraphrased with attribution) and Mayo Clinic (linked reference only, no text used); ICD-10 and labels from Wikidata (CC0).

Emergency — call📞 102