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Sofosbuvir

Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor, Hepatitis C Virus NS5A Inhibitor, Hepatitis C Virus NS3/4A Protease Inhibitor

WHO आवश्यक दवा EML अनुभाग: Pangenotypic direct-acting antiviral combinations

यह केवल जानकारी है, प्रिस्क्रिप्शन नहीं। कोई भी दवा लेने से पहले डॉक्टर या फार्मासिस्ट से सलाह लें। ओवरडोज़/विषाक्तता पर 102 पर कॉल करें।

ब्रांड नाम

Nepal brand names not included: no licence-safe source.

What it is used for

is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor. genotype 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor.

Common side effects

The following serious adverse reactions are described below and elsewhere in labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse reactions (incidence greater than or equal to 10%, all grades) observed with treatment with VOSEVI for 12 weeks were headache, fatigue, diarrhea, and nausea.

Do not use if (contraindications)

is contraindicated with rifampin. Coadministration with rifampin.

Pregnancy & breastfeeding

Pregnancy (label summary): Risk Summary No adequate human data are available to establish whether or not VOSEVI poses a risk to pregnancy outcomes.

ओवरडोज़ या विषाक्तता

ओवरडोज़/विषाक्तता की आशंका पर अभी 102 पर कॉल करें।

102

सामान्य प्रश्न

What is Sofosbuvir used for?
is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor.

What are the side effects of Sofosbuvir?
The following serious adverse reactions are described below and elsewhere in labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse reactions (incidence greater than or equal to 10%, all grades) observed with treatment with VOSEVI for 12 weeks were headache, fatigue,...

Who should not take Sofosbuvir?
is contraindicated with rifampin. Coadministration with rifampin.

Does Sofosbuvir have a boxed warning?
RISK OF HEPATITIS B VIRUS REACTIVATION IN PATIENTS COINFECTED WITH HCV AND HBV Test all patients for evidence of current or prior hepatitis B virus (HBV) infection before initiating treatment with VOSEVI.

Can I take Sofosbuvir in pregnancy or while breastfeeding?
Pregnancy (label summary): Risk Summary No adequate human data are available to establish whether or not VOSEVI poses a risk to pregnancy outcomes.

What is the dose of Sofosbuvir?
Not provided here. Ask a doctor or pharmacist.

Sofosbuvir क्या है?
Sofosbuvir is used for: is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor. ge…

Sofosbuvir के दुष्प्रभाव क्या हैं?
The following serious adverse reactions are described below and elsewhere in labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse reactions (incidence greater than or equal to 10%, all grades) observed with treatment with VOSEVI for 12 weeks were headache, fatigue, d…

स्रोत: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference

US FDA DailyMed; NLM RxNorm

आपात — कॉल102