💊 This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.
Simvastatin is a medication that works by inhibiting an enzyme called HMG-CoA reductase. This enzyme is crucial in the process of making cholesterol. By inhibiting this enzyme, simvastatin reduces the production of cholesterol in the body. This can help lower blood cholesterol levels, which is beneficial for maintaining heart health. Simvastatin is typically used to treat high cholesterol levels and reduce the risk of heart disease. It is important to consult a healthcare professional before starting this medication, as it can have potential side effects and interactions with other drugs.
Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference
Simvastatin is a prodrug and is hydrolyzed to its active β-hydroxyacid form, simvastatin acid, after administration. Simvastatin acid and its metabolites are inhibitors of HMG-CoA reductase, the rate-limiting enzyme that converts HMG-CoA to mevalonate, a precursor of cholesterol.
For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.
📞 Call 102Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference
US FDA DailyMed; NLM RxNorm