Bevacizumab

ब्रान्ड नाम

Nepal brand names not included: no licence-safe source.

What it is used for

is a vascular endothelial growth factor inhibitor indicated for the treatment of: Metastatic colorectal cancer, in combination with intravenous fluorouracil-based chemotherapy for first- or second-line treatment.

How it works

Bevacizumab products bind VEGF and prevent the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in in vitro models of angiogenesis.

Common side effects

The following clinically significant adverse reactions are described elsewhere in the labeling: Gastrointestinal Perforations and Fistulae. Surgery and Wound Healing Complications. Hemorrhage. Arterial Thromboembolic Events. Venous Thromboembolic Events. Hypertension. Posterior Reversible Encephalopathy Syndrome.

Do not use if (contraindications)

None. None

Pregnancy & breastfeeding

Pregnancy (label summary): Risk Summary Based on findings from animal studies and their mechanism of action, bevacizumab products may cause fetal harm in pregnant women.

सामान्य प्रश्न

What is Bevacizumab used for?
is a vascular endothelial growth factor inhibitor indicated for the treatment of: Metastatic colorectal cancer, in combination with intravenous fluorouracil-based chemotherapy for first- or second-line treatment.

How does Bevacizumab work?
Bevacizumab products bind VEGF and prevent the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in in vitro models of angiogenesis.

What are the side effects of Bevacizumab?
The following clinically significant adverse reactions are described elsewhere in the labeling: Gastrointestinal Perforations and Fistulae. Surgery and Wound Healing Complications. Hemorrhage. Arterial Thromboembolic Events. Venous Thromboembolic Events. Hypertension.

Who should not take Bevacizumab?
None. None

Can I take Bevacizumab in pregnancy or while breastfeeding?
Pregnancy (label summary): Risk Summary Based on findings from animal studies and their mechanism of action, bevacizumab products may cause fetal harm in pregnant women.

What is the dose of Bevacizumab?
Not provided here. Ask a doctor or pharmacist.

Bevacizumab के हो?
Bevacizumab is used for: is a vascular endothelial growth factor inhibitor indicated for the treatment of: Metastatic colorectal cancer, in combination with intravenous fluorouracil-based chemotherapy for first- or second-line treatment. It belongs to the class: Vascular Endothelial Growth Factor Inhibitor. Common s…

Bevacizumab कसरी काम गर्छ?
Bevacizumab products bind VEGF and prevent the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in in vitro models of angiogenesis.