DigiNepal
Alfred G. Gilman
NIH historic image · Public domain
Suggest a better photo · Report

Alfred G. Gilman

American pharmacologist (1941-2015)

नेपालीमा पढ्नुहोस् · हिंदी में पढ़ें

  • नेपाली · English · हिंदीRead in your language
  • CitedEvery fact sourced
  • Ad-freeNo ads, no tracking

Alfred Goodman Gilman (July 1, 1941 – December 23, 2015) was an American pharmacologist and biochemist. He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells."

Quick facts

Born
wd
Place of birth
New Haven wd
Died
wd
Place of death
Dallas wd
Citizenship
United States wd
Occupation
pharmacologist, pharmacist, university teacher, biochemist, physiologist wd
Education
Yale University, University of Virginia, Case Western Reserve University wd

Awards wd

  • Albert Lasker Award for Basic Medical Research (1989)
  • Nobel Prize in Physiology or Medicine (1994)
  • Canada Gairdner International Award (1984)
  • Louisa Gross Horwitz Prize (1989)
  • John J. Abel Award (1975)
  • Richard Lounsbery Award (1987)
  • honorary doctor of the University of Miami (1999)

About

Gilman was the son of Alfred Gilman, who co-authored Goodman & Gilman's The Pharmacological Basis of Therapeutics with Louis S. Goodman, from whom his middle name came. He earned a BA in biology with major in biochemistry from Yale University. Immediately after graduation in 1962, he worked with Allan Conney at Burroughs Wellcome & Company, which resulted in the publication of his first two technical papers. Persuaded by Earl Wilbur Sutherland, Jr., he joined Case Western Reserve University School of Medicine for an MD–PhD course. He obtained his degree in 1969. He then went to the National Institutes of Health to work with Marshall Nirenberg between 1969 and 1971.

Gilman became assistant professor of pharmacology at the University of Virginia School of Medicine in 1971, and full professor in 1977. He chaired the Department of Pharmacology at the University of Texas Southwestern Medical Center at Dallas from 1981. Upon his retirement in 2009, he was appointed chief scientific officer of the Cancer Prevention and Research Institute of Texas. He resigned in 2012. He was the founder of Regeneron Pharmaceuticals company and the Alliance for Cellular Signaling. From 2005, he was also director of Eli Lilly and Company.

G proteins are a vital intermediary between the extracellular activation of receptors (G protein-coupled receptors) on the cell membrane and actions within the cell. Rodbell had shown in the 1960s that GTP was involved in cell signaling. It was Gilman who actually discovered the proteins that interacted with the GTP to initiate signalling cascades within the cell, and thus,…

Questions

When was Alfred G. Gilman born?
Alfred G. Gilman was born on 1 July 1941 in New Haven.
Where did Alfred G. Gilman study?
Alfred G. Gilman was educated at Yale University, University of Virginia, Case Western Reserve University.

Sources

  1. Wikipedia (English): Alfred G. Gilman · CC BY-SA 4.0
  2. Wikidata item Q296423 · CC0 1.0
  3. Image: Alfred Goodman Gilman (cropped).jpg by NIH historic image (Public domain)

Last updated · facts checked 4 November 2026

Cite this page

"Alfred G. Gilman". DigiNepal. Last updated 31 October 2026. https://diginpl.com/people/alfred-g-gilman. Retrieved 4 November 2026.

Machine-readable versions: JSON · Markdown

Text from the Wikipedia article Alfred G. Gilman, licensed under CC BY-SA 4.0. This page's text is shared under the same licence. Facts from Wikidata (CC0). Image: Alfred Goodman Gilman (cropped).jpg — NIH historic image, Public domain.

Is this you, or do you work in this person's office? Claim this profile

← People