DigiNepal · drugs
Sofosbuvir is used for: is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor. genotype 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor. It belongs to the class: Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor, Hepatitis C Virus NS5A Inhibitor, Hepatitis C Virus NS3/4A Protease Inhibitor. Common side effects include: The following serious adverse reactions are described below and elsewhere in labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. Sofosbuvir. Used for (FDA label): is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor. genotype 1a or 3 infection and have previously been treated with an HCV regimen containing sofosbuvir without an NS5A inhibitor. Boxed warning: RISK OF HEPATITIS B VIRUS REACTIVATION IN PATIENTS COINFECTED WITH HCV AND HBV Test all patients for evidence of current or prior hepatitis B virus (HBV) infection before initiating treatment with VOSEVI. Do not use if: is contraindicated with rifampin. Coadministration with rifampin. Common side effects: The following serious adverse reactions are described below and elsewhere in labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse reactions (incidence greater than or equal to 10%, all grades) observed with treatment with VOSEVI for 12 weeks were headache, fatigue, diarrhea, and nausea. Pregnancy (label summary): Risk Summary No adequate human data are available to establish whether or not VOSEVI poses a risk to pregnancy outcomes. General information only, not medical advice and not a prescription. No doses are given. Always consult a doctor or pharmacist before starting, stopping or changing any medicine, especially in pregnancy, breastfeeding, children, older age or with other medicines.