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HLA-B27

The HLA-B27 looks at a genetic marker linked to spine arthritis. It is done for: young people with inflammatory back pain.

General health information, not a diagnosis. In an emergency, call 102. Always consult a qualified health professional.

Why it is done

Young people with inflammatory back pain.

Preparation

No fasting needed. Laboratory-specific; see the reference range on your report. High or positive may mean: Supports ankylosing spondylitis with symptoms. Low or negative may mean: Less likely. General information, not a diagnosis. Results must be interpreted by a qualified health worker.

What it measures

A genetic marker linked to spine arthritis.

Sample type

Blood

If the result is high

Supports ankylosing spondylitis with symptoms.

If the result is low

Less likely.

Reference ranges vary by lab, age and sex — always use the range printed on your own report.

Consult a doctor to interpret results — a single test does not make a diagnosis.

Where to get this near you

Care near you

Uses your location once to list the nearest facilities. Nothing is stored.

Common questions

What does the HLA-B27 measure?
A genetic marker linked to spine arthritis.

Why is the HLA-B27 done?
Young people with inflammatory back pain.

Do I need to fast for the HLA-B27?
No fasting needed.

What does a high or positive HLA-B27 mean?
Supports ankylosing spondylitis with symptoms.

What does a low or negative HLA-B27 mean?
Less likely.

What is the normal range for the HLA-B27?
Laboratory-specific; see the reference range on your report.

Why is HLA-B27 done?
Young people with inflammatory back pain.

Do I need to prepare or fast for HLA-B27?
No fasting needed. Laboratory-specific; see the reference range on your report. High or positive may mean: Supports ankylosing spondylitis with symptoms. Low or negative may mean: Less likely. General information, not a diagnosis. Results must be interpreted by a qualified health worker.

SI text CC BY 4.0; decoder reference data (cited per range); LOINC codes free with attribution (notice included).

Sources: SI health summary (own words); MedlinePlus Lab Tests and CDC as references

Emergency — call102