WHO Essential Medicine EML section: Hormones and antihormones
This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.
UTERINE MALIGNANCIES and THROMBOEMBOLIC EVENTS Serious and life-threatening events from the use of SOLTAMOX include uterine malignancies, stroke, and pulmonary embolism. Fatal cases of each type of event have occurred.
Nepal brand names not included: no licence-safe source.
is an estrogen agonist/antagonist indicated: For treatment of adult patients with estrogen receptor-positive metastatic breast cancer For adjuvant treatment of adult patients with early stage estrogen receptor- positive breast cancer To reduce risk of invasive breast cancer following breast surgery and radiation in adult women with ductal carcinoma in situ (DCIS) To reduce the incidence of breast cancer in adult...
Tamoxifen is an estrogen agonist/antagonist. Tamoxifen competes with estrogen for binding to the estrogen receptor, which can result in a decrease in estrogen receptor signaling-dependent growth in breast tissue.
The following serious adverse reactions are discussed below and elsewhere in the labeling: Uterine malignancies Thromboembolic events Embryo-Fetal Toxicity Liver cancer Most common adverse reactions: hot flashes, mood disturbances, vaginal discharge, vaginal bleeding, nausea, and fluid retention.
is contraindicated in patients with known hypersensitivity (e.g., angioedema, serious skin reactions) to tamoxifen or any other SOLTAMOX ingredient.
Pregnancy (label summary): Risk Summary SOLTAMOX can cause fetal harm when administered to a pregnant woman. There are no adequate and well- controlled studies of tamoxifen in pregnant women.
For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.
Call 102What is Tamoxifen used for?
is an estrogen agonist/antagonist indicated: For treatment of adult patients with estrogen receptor-positive metastatic breast cancer For adjuvant treatment of adult patients with early stage estrogen receptor- positive breast cancer To reduce risk of invasive breast cancer following breast surgery and radiation in...
How does Tamoxifen work?
Tamoxifen is an estrogen agonist/antagonist. Tamoxifen competes with estrogen for binding to the estrogen receptor, which can result in a decrease in estrogen receptor signaling-dependent growth in breast tissue.
What are the side effects of Tamoxifen?
The following serious adverse reactions are discussed below and elsewhere in the labeling: Uterine malignancies Thromboembolic events Embryo-Fetal Toxicity Liver cancer Most common adverse reactions: hot flashes, mood disturbances, vaginal discharge, vaginal bleeding, nausea, and fluid retention.
Who should not take Tamoxifen?
is contraindicated in patients with known hypersensitivity (e.g., angioedema, serious skin reactions) to tamoxifen or any other SOLTAMOX ingredient.
Does Tamoxifen have a boxed warning?
UTERINE MALIGNANCIES and THROMBOEMBOLIC EVENTS Serious and life-threatening events from the use of SOLTAMOX include uterine malignancies, stroke, and pulmonary embolism. Fatal cases of each type of event have occurred.
Can I take Tamoxifen in pregnancy or while breastfeeding?
Pregnancy (label summary): Risk Summary SOLTAMOX can cause fetal harm when administered to a pregnant woman. There are no adequate and well- controlled studies of tamoxifen in pregnant women.
What is the dose of Tamoxifen?
Not provided here. Ask a doctor or pharmacist.
What is Tamoxifen?
Tamoxifen is used for: is an estrogen agonist/antagonist indicated: For treatment of adult patients with estrogen receptor-positive metastatic breast cancer For adjuvant treatment of adult patients with early stage estrogen receptor- positive breast cancer To reduce risk of invasive breast cancer following breast su…
Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference
US FDA DailyMed; NLM RxNorm