DigiNepal Health ENनेहि

← Health · Medicines

Sodium Nitroprusside

WHO Essential Medicine EML section: Antihypertensive medicines

This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.

Brand names

Nepal brand names not included: no licence-safe source.

What it is used for

INDICATIONS & USAGE Sodium nitroprusside is indicated for the immediate reduction of blood pressure of adult and pediatric patients in hypertensive crises. Concomitant longer-acting antihypertensive medication should be administered so that the duration of treatment with sodium nitroprusside can be minimized.

Common side effects

The most important adverse reactions to sodium nitroprusside are the avoidable ones of excessive hypotension and cyanide toxicity, described above under WARNINGS. The adverse reactions described in this section develop less rapidly and, as it happens, less commonly.

Do not use if (contraindications)

Sodium nitroprusside should not be used in the treatment of compensatory hypertension, where the primary hemodynamic lesion is aortic coarctation or arteriovenous shunting.

Pregnancy & breastfeeding

Pregnancy (label summary): Teratogenic effects: Pregnancy Category C. There are no adequate, well-controlled studies of sodium nitroprusside injection in either laboratory animals or pregnant women. Breastfeeding (label summary): NURSING MOTHERS It is not known whether sodium nitroprusside and its metabolites are excreted in human milk.

Overdose or poisoning

For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.

Call 102

Common questions

What is Sodium Nitroprusside used for?
INDICATIONS & USAGE Sodium nitroprusside is indicated for the immediate reduction of blood pressure of adult and pediatric patients in hypertensive crises. Concomitant longer-acting antihypertensive medication should be administered so that the duration of treatment with sodium nitroprusside can be minimized.

What are the side effects of Sodium Nitroprusside?
The most important adverse reactions to sodium nitroprusside are the avoidable ones of excessive hypotension and cyanide toxicity, described above under WARNINGS. The adverse reactions described in this section develop less rapidly and, as it happens, less commonly.

Who should not take Sodium Nitroprusside?
Sodium nitroprusside should not be used in the treatment of compensatory hypertension, where the primary hemodynamic lesion is aortic coarctation or arteriovenous shunting.

Does Sodium Nitroprusside have a boxed warning?
Sodium nitroprusside injection is not suitable for direct injection. The solution must be further diluted in sterile 5% dextrose injection before infusion. In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death.

Can I take Sodium Nitroprusside in pregnancy or while breastfeeding?
Pregnancy (label summary): Teratogenic effects: Pregnancy Category C. There are no adequate, well-controlled studies of sodium nitroprusside injection in either laboratory animals or pregnant women.

What is the dose of Sodium Nitroprusside?
Not provided here. Ask a doctor or pharmacist.

What is Sodium Nitroprusside?
Sodium Nitroprusside is used for: INDICATIONS & USAGE Sodium nitroprusside is indicated for the immediate reduction of blood pressure of adult and pediatric patients in hypertensive crises. Common side effects include: The most important adverse reactions to sodium nitroprusside are the avoidable ones of excessive h…

Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference

US FDA DailyMed; NLM RxNorm

Emergency — call102