Microtubule Inhibitor
WHO Essential Medicine EML section: Cytotoxic medicines
This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.
Paclitaxel should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of complications is possible only when adequate diagnostic and treatment facilities are readily available.
Nepal brand names not included: no licence-safe source.
Paclitaxel Injection, USP is indicated as subsequent therapy for the treatment of advanced carcinoma of the ovary. As first-line therapy, Paclitaxel Injection, USP is indicated in combination with cisplatin. Paclitaxel Injection, USP is indicated for the adjuvant treatment of node-positive breast cancer administered sequentially to standard doxorubicin-containing combination chemotherapy.
Pooled Analysis of Adverse Event Experiences from Single-Agent Studies Data in the following table are based on the experience of 812 patients (493 with ovarian carcinoma and 319 with breast carcinoma) enrolled in 10 studies who received single-agent Paclitaxel Injection. TABLE 10. b All patients received premedication.
Paclitaxel is contraindicated in patients who have a history of hypersensitivity reactions to paclitaxel or other drugs formulated in polyoxyl 35 castor oil.
Pregnancy (label summary): (See WARNINGS section). Breastfeeding (label summary): Nursing Mothers It is not known whether the drug is excreted in human milk.
For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.
Call 102What is Paclitaxel used for?
Paclitaxel Injection, USP is indicated as subsequent therapy for the treatment of advanced carcinoma of the ovary. As first-line therapy, Paclitaxel Injection, USP is indicated in combination with cisplatin.
What are the side effects of Paclitaxel?
Pooled Analysis of Adverse Event Experiences from Single-Agent Studies Data in the following table are based on the experience of 812 patients (493 with ovarian carcinoma and 319 with breast carcinoma) enrolled in 10 studies who received single-agent Paclitaxel Injection. TABLE 10.
Who should not take Paclitaxel?
Paclitaxel is contraindicated in patients who have a history of hypersensitivity reactions to paclitaxel or other drugs formulated in polyoxyl 35 castor oil.
Does Paclitaxel have a boxed warning?
Paclitaxel should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of complications is possible only when adequate diagnostic and treatment facilities are readily available.
Can I take Paclitaxel in pregnancy or while breastfeeding?
Pregnancy (label summary): (See WARNINGS section). Breastfeeding (label summary): Nursing Mothers It is not known whether the drug is excreted in human milk.
What is the dose of Paclitaxel?
Not provided here. Ask a doctor or pharmacist.
What is Paclitaxel?
Paclitaxel is used for: Paclitaxel Injection, USP is indicated as subsequent therapy for the treatment of advanced carcinoma of the ovary. It belongs to the class: Microtubule Inhibitor. Common side effects include: Pooled Analysis of Adverse Event Experiences from Single-Agent Studies Data in the following table ar…
Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference
US FDA DailyMed; NLM RxNorm