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Medroxyprogesterone Acetate

WHO Essential Medicine EML section: Progestogens

This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.

Brand names

Nepal brand names not included: no licence-safe source.

What it is used for

Medroxyprogesterone acetate injectable suspension is indicated for use by females of reproductive potential to prevent pregnancy. Limitations of Use: The use of medroxyprogesterone acetate injectable suspension is not recommended as a long-term (i.e., longer than 2 years) birth control method unless other options are considered inadequate.

How it works

Medroxyprogesterone acetate (MPA) injectable suspension, inhibits the secretion of gonadotropins which primarily prevents follicular maturation and ovulation and causes thickening of cervical mucus. These actions contribute to its contraceptive effect.

Common side effects

The following important adverse reactions observed with the use of medroxyprogesterone acetate injectable suspension are discussed in greater detail in the Warnings and Precautions section: Loss of Bone Mineral Density Thromboembolic disease Breast Cancer Anaphylaxis and Anaphylactoid Reactions Bleeding Irregularities Weight Gain Most common...

Do not use if (contraindications)

The use of medroxyprogesterone acetate injectable suspension is contraindicated in the following conditions: Known or suspected pregnancy or as a diagnostic test for pregnancy. Active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease.

Pregnancy & breastfeeding

Pregnancy (label summary): Medroxyprogesterone acetate injectable suspension should not be administered during pregnancy. [ See Contraindications and Warnings and Precautions ( 5.1 7).] Breastfeeding (label summary): 8.3 Nursing Mothers Detectable amounts of drug have been identified in the milk of mothers receiving medroxyprogesterone acetate injectable suspension. [ See Warnings and Precautions ( 5.1 3).]

Overdose or poisoning

For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.

Call 102

Common questions

What is Medroxyprogesterone Acetate used for?
Medroxyprogesterone acetate injectable suspension is indicated for use by females of reproductive potential to prevent pregnancy. Limitations of Use: The use of medroxyprogesterone acetate injectable suspension is not recommended as a long-term (i.e., longer than 2 years) birth control method unless other options are...

How does Medroxyprogesterone Acetate work?
Medroxyprogesterone acetate (MPA) injectable suspension, inhibits the secretion of gonadotropins which primarily prevents follicular maturation and ovulation and causes thickening of cervical mucus. These actions contribute to its contraceptive effect.

What are the side effects of Medroxyprogesterone Acetate?
The following important adverse reactions observed with the use of medroxyprogesterone acetate injectable suspension are discussed in greater detail in the Warnings and Precautions section: Loss of Bone Mineral Density Thromboembolic disease Breast Cancer Anaphylaxis and Anaphylactoid Reactions Bleeding...

Who should not take Medroxyprogesterone Acetate?
The use of medroxyprogesterone acetate injectable suspension is contraindicated in the following conditions: Known or suspected pregnancy or as a diagnostic test for pregnancy. Active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease.

Does Medroxyprogesterone Acetate have a boxed warning?
LOSS OF BONE MINERAL DENSITY Women who use medroxyprogesterone acetate injectable suspension may lose significant bone mineral density. Bone loss is greater with increasing duration of use and may not be completely reversible.

Can I take Medroxyprogesterone Acetate in pregnancy or while breastfeeding?
Pregnancy (label summary): Medroxyprogesterone acetate injectable suspension should not be administered during pregnancy. [ See Contraindications and Warnings and Precautions ( 5.1 7).] Breastfeeding (label summary): 8.3 Nursing Mothers Detectable amounts of drug have been identified in the milk of mothers receiving...

What is the dose of Medroxyprogesterone Acetate?
Not provided here. Ask a doctor or pharmacist.

What is Medroxyprogesterone Acetate?
Medroxyprogesterone Acetate is used for: Medroxyprogesterone acetate injectable suspension is indicated for use by females of reproductive potential to prevent pregnancy. Common side effects include: The following important adverse reactions observed with the use of medroxyprogesterone acetate injectable suspension …

Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference

US FDA DailyMed; NLM RxNorm

Emergency — call102