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Ketamine

WHO Essential Medicine EML section: Injectable medicines

This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.

Brand names

Nepal brand names not included: no licence-safe source.

What it is used for

(ketamine hydrochloride) injection is indicated: as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. for the induction of anesthesia prior to the administration of other general anesthetic agents. as a supplement to other anesthetic agents.

How it works

KETALAR, a racemic mixture of ketamine, is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor. The major circulating metabolite of ketamine (norketamine) demonstrated activity at the same receptor with less affinity.

Common side effects

The following clinically significant adverse reactions are described elsewhere in the labeling: Hemodynamic Instability Emergence Reactions Respiratory Depression Pediatric Neurotoxicity Drug-Induced Liver Injury The following adverse reactions associated with the use of KETALAR were identified in clinical studies or postmarketing reports.

Do not use if (contraindications)

is contraindicated in patients for whom a significant elevation of blood pressure would constitute a serious hazard. KETALAR is contraindicated in patients with known hypersensitivity to ketamine or to any excipient.

Pregnancy & breastfeeding

Pregnancy (label summary): Risk Summary Available data on the use of ketamine in pregnant women mostly describe its use at the time of cesarean section and have not identified a drug-associated risk of adverse maternal or fetal outcomes.

Overdose or poisoning

For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.

Call 102

Common questions

What is Ketamine used for?
(ketamine hydrochloride) injection is indicated: as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. for the induction of anesthesia prior to the administration of other general anesthetic agents. as a supplement to other anesthetic agents.

How does Ketamine work?
KETALAR, a racemic mixture of ketamine, is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor. The major circulating metabolite of ketamine (norketamine) demonstrated activity at the same receptor with less affinity.

What are the side effects of Ketamine?
The following clinically significant adverse reactions are described elsewhere in the labeling: Hemodynamic Instability Emergence Reactions Respiratory Depression Pediatric Neurotoxicity Drug-Induced Liver Injury The following adverse reactions associated with the use of KETALAR were identified in clinical studies or...

Who should not take Ketamine?
is contraindicated in patients for whom a significant elevation of blood pressure would constitute a serious hazard. KETALAR is contraindicated in patients with known hypersensitivity to ketamine or to any excipient.

Can I take Ketamine in pregnancy or while breastfeeding?
Pregnancy (label summary): Risk Summary Available data on the use of ketamine in pregnant women mostly describe its use at the time of cesarean section and have not identified a drug-associated risk of adverse maternal or fetal outcomes.

What is the dose of Ketamine?
Not provided here. Ask a doctor or pharmacist.

What is Ketamine?
Ketamine is used for: (ketamine hydrochloride) injection is indicated: as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. for the induction of anesthesia prior to the administration of other general anesthetic agents. as a supplement to other anestheti…

Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference

US FDA DailyMed; NLM RxNorm

Emergency — call102