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Efavirenz

Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor

WHO Essential Medicine EML section: Non-nucleoside reverse transcriptase inhibitors

This is information only, not a prescription. Talk to a doctor or pharmacist before taking any medicine. For an overdose or poisoning, call 102.

Brand names

Nepal brand names not included: no licence-safe source.

What it is used for

& USAGE Efavirenz in combination with other antiretroviral agents is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and in pediatric patients at least 3 months old and weighing at least 3.5 kg.

How it works

Efavirenz is an antiviral drug.

Common side effects

The most significant adverse reactions observed in patients treated with efavirenz are: •psychiatric symptoms, •nervous system symptoms, •rash. •hepatotoxicity Most common adverse reactions (>5%, moderate-severe) are impaired concentration, abnormal dreams, rash, dizziness, nausea, headache, fatigue, insomnia, and vomiting.

Do not use if (contraindications)

• Efavirenz is contraindicated in patients with previously demonstrated clinically significant hypersensitivity (e.g., Stevens-Johnson syndrome, erythema multiforme, or toxic skin eruptions) to any of the components of this product.

Pregnancy & breastfeeding

Pregnancy (label summary): Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to efavirenz during pregnancy. Physicians are encouraged to register patients by calling the Antiretroviral Pregnancy Registry at 1-800-258-4263.

Overdose or poisoning

For a suspected overdose or poisoning, call 102 now and go to the nearest emergency hospital.

Call 102

Common questions

What is Efavirenz used for?
& USAGE Efavirenz in combination with other antiretroviral agents is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and in pediatric patients at least 3 months old and weighing at least 3.5 kg.

How does Efavirenz work?
Efavirenz is an antiviral drug.

What are the side effects of Efavirenz?
The most significant adverse reactions observed in patients treated with efavirenz are: •psychiatric symptoms, •nervous system symptoms, •rash. •hepatotoxicity Most common adverse reactions (>5%, moderate-severe) are impaired concentration, abnormal dreams, rash, dizziness, nausea, headache, fatigue, insomnia, and...

Who should not take Efavirenz?
• Efavirenz is contraindicated in patients with previously demonstrated clinically significant hypersensitivity (e.g., Stevens-Johnson syndrome, erythema multiforme, or toxic skin eruptions) to any of the components of this product.

Can I take Efavirenz in pregnancy or while breastfeeding?
Pregnancy (label summary): Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to efavirenz during pregnancy. Physicians are encouraged to register patients by calling the Antiretroviral Pregnancy Registry at 1-800-258-4263.

What is the dose of Efavirenz?
Not provided here. Ask a doctor or pharmacist.

What is Efavirenz?
Efavirenz is used for: & USAGE Efavirenz in combination with other antiretroviral agents is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and in pediatric patients at least 3 months old and weighing at least 3.5 kg. It belongs to the class: Human Immunodeficiency Viru…

Sources: FDA SPL label (openFDA/DailyMed); RxNorm (NLM) · Reference · Reference · Reference

US FDA DailyMed; NLM RxNorm

Emergency — call102